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SerinAid® by Chemi Nutra is a trademarked form of phosphatidylserine (PS), one of the most well-known brain-supporting nutrients in the world. PS has been researched in over 40 human clinical trials, including 20+ placebo-controlled trials over the last 30 years. Phosphatidylserine plays a critical role in both maintaining and improving cognitive performance, focus, memory, and concentration and can also improve attention and mood [1-10].* In addition, SerinAid® PS reduces elevated cortisol levels, stress levels, and improves athletic performance.* Phosphatidylserine is a structural component of the neuronal cell membrane, the organelle that regulates the flow of nutrients and compounds into and out of a cell and maintains cellular integrity.* Therefore, SerinAid® can also promote healthy membranes, intracellular communication, and brain health.*

A branded ingredient of FutureCeuticals Inc., ElevATP® is proven clinically to endogenously increase ATP levels to boost athletic performance and strength while decreasing performance decrements with overtraining [11].* ElevATP® improves mitochondrial function by raising ATP levels, the crucial energy carrier in our cells [12].* As we age, our ability to produce ATP declines substantially. Therefore, an ingredient like ElevATP® can play a role in getting you back on track. ElevATP® is composed of a water extract of ancient peat that contains over 70 trace minerals including sulfur, magnesium, manganese, calcium, phosphorus, potassium, zinc, silicon, iron, and more [13].* Similar to Shilajit Resin found in the rocks of the himalayas, ElevATP® boosts vitality and supports adaptivity.* ElevATP® also contains an apple peel extract with ten unique apple polyphenols, compounds that have beneficial effects on your gut biome. *

Created by Sabinsa Corporation, BioPerine® is a clinically proven enhancer of bioavailability.* A vital part of our formula, it maximizes your absorption of the compounds and vitamins our blends contain.* BioPerine® is a 95% standardized extract of piperine from the black pepper plant. It is the only source of piperine that has been clinically studied extensively for safety and efficacy. It enhances the absorption vitamins A, B complex, C, D, E, K, amino acids, antioxidants, herbal extracts, and more.* Of particular importance to our formula, BioPerine® has been found to enhance the bioavailability of resveratrol 229% and boosts its max serum levels 1544% in animal studies making it a key ingredient in our formulations [14].*

SelenoExcell®, a special trademarked ingredient of Cypress Systems Inc., is derived from a high selenium yeast called Saccharomyces cerevisiae. Compared to most supplements that only contain one form, the selenium derived from this yeast contains all three forms of organic selenium: selenocysteine, selenomethionine, and methylselenocysteine. A recent study has shown organic selenium derived from yeast containing all three forms to be highly effective in counteracting free radical damage compared to the individual selenomethionine form [15].* Another study showed a correlation between higher dietary intake of selenium and longer telomere length [16].* In addition, selenium is a vital trace mineral that plays many roles in the body, from supporting heart health to being a crucial cofactor for powerful antioxidant enzymes such as glutathione peroxidase.*

A famous polyphenol found in grapes and red wine, resveratrol has been the subject of over 12,000+ scientific studies. Resveratrol can activate SIRT-1 and AMPK, which both play a crucial role in how we age [17-27].* Resveratrol also acts as a caloric restriction mimetic, which means it stimulates the health effects of calorie restriction and provides similar benefits to intermittent fasting and lengthens life spans across various species [27, 28].* Resveratrol is beneficial for cardiovascular health due to its potent antioxidant capabilities [18, 20, 28].* As a polyphenol, Resveratrol works synergistically with other polyphenols in Wellness such as pterostilbene and the ten apple polyphenols in ElevATP®.* Our formula maximizes the absorption of Resveratrol with BioPerine®. BioPerine® improves its bioavailability up to 229% and maximum serum levels up to 1544% in animal studies [14].*

Berberine is most well-known for its ability to support healthy glucose metabolism [29-35].* Historically used in Traditional Chinese Medicine, this yellow compound has a range of benefits for your health. Berberine also supports reduced advanced glycation end products, unhealthy compounds that can cause chronic oxidative damage and aging [36-39].* It can also activate the master metabolic control switch, AMPK [40-42].* AMPK activation can increase both ATP and NAD+ levels, which are crucial energy molecules necessary for healthy living and aging.*

One of the most potent antioxidants known to man – Astaxanthin is 6000 times more effective than vitamin C and 800 times more effective than CoQ10 at quenching free radicals [43].* Astaxanthin is also more potent than its fellow carotenoids lutein and zeaxanthin in terms of its antioxidant power [43].* As an antioxidant, astaxanthin promotes cellular integrity and reduces free radical damage in the body and skin, supporting healthy skin elasticity [44-45].* Because of its ability to cross the blood-retina barrier, astaxanthin promotes healthy vision and reduced eye strain [46-48].* Also, there is evidence from human and animal studies that astaxanthin crosses the blood-brain barrier and supports brain health [49-53].*

Alpha-glyceryl phosphorylcholine is a nootropic form of choline, a vital brain nutrient. Unlike choline bitartrate, Alpha-GPC is a powerful brain nutrient due to its ability to cross the blood-brain barrier. Choline, the end product of Alpha-GPC, plays a vital role in brain health, brain development, cognition, memory, mood, and liver function [54-62].* In the brain, choline is involved in the production of the acetylcholine, a neurotransmitter crucial for memory, intelligence, mood, and cognitive function.* Choline is also a critical component of cell membranes in both the brain and the body, and cellular membranes are vital components of cellular integrity and function [63].* There is also evidence Alpha-GPC can also increase maximum power and velocity in athletic performance tasks [64-67].*

Bacopa, also known as “Brahmi”, is an adaptogenic and nootropic herb that can help promote healthy responses to stress and improve mental performance*. It has been shown in some scientific studies to enhance memory retention, attention span, focus and learning [70-75].* Bacopa contains compounds known as bacosides which have various beneficial effects on cognitive function and dendritic formation.* Our formula has a high potency form with 40% bacosides/bacopasides, the active compounds with the cognition boosting benefits.*

Quercetin is an antioxidant, flavanol, and polyphenol found in leafy greens, berries, broccoli, apples, green tea, and grapes. We use the quercetin dihydrate form, in contrast to regular quercetin, which has much lower bioavailability. Quercetin dihydrate is significantly more expensive, but is absorbed and used much more readily by the body, thus giving you the optimal benefits.* Quercetin has a range of benefits for your health and your gut bacteria. Quercetin promotes gut bacterial diversity by providing fuels for good bacteria to metabolize as well as strength for intestinal barrier function [29-30].* Quercetin is metabolized by your gut bacteria into phenolic acids, which are potent antioxidant compounds that benefit your health [31-35].* As an antioxidant, quercetin can quench free radicals in the body protecting cells from oxidative damage and support cardiovascular health [36-37].* Quercetin can also promote healthy aging through several other mechanisms including the reduction of advanced glycation end-products and effects on aged, senescent cells [38-41].* Advanced glycation end products are damaging molecules that form when proteins or fats combine with sugars and contribute to aging, inflammation, and oxidative stress [42-45]. *

Vitamin D is an integral vitamin that we get from the sun and our diets. Our Vitamin D3 (VegD3®) has a proven clean supply chain, clean sourcing, and is vegan society approved! Our D3 is sourced from micro-algae unlike the sticky greasy secretions of sheep's sebaceous glands that most Vitamin D's on the market are from(gross!). Vitamin D has been shown to play a vital role in maintaining and protecting your gut barrier which promotes decreased inflammation [103-113].* Vitamin D also plays an important role in healthy calcium and phosphorus metabolism in the body and in the production of strong and healthy bones.* In addition, several studies have also shown an association between higher Vitamin D and longer telomere lengths, the protective caps on the ends of our chromosomes (genetic material) that progressively shorten as we age [114-116].* There is also some evidence for the role of vitamin D in immunity, brain function, and mood [117]. *

Our folate is found in the active methylated form, which is crucial since up to 40% of the population or more has a genetic mutation not allowing them to convert folate to its active form efficiently. Folate is an essential vitamin for pregnant women, healthy DNA synthesis, repair, and expression, as well red blood cell production.* Healthy levels of folate in the brain can play a role in a healthy mood and synapses and the activated form is crucial for the production of serotonin in the brain.* Along with vitamin B6 and B12, folate is also necessary for the recycling of homocysteine from the blood.*

B-complex: includes B1, B2, B3, B5, B6, B7, B9, and B12, crucial vitamins for metabolism, health, and energy production. In addition, each has its own benefits.

Vitamin B1 (as thiamine): Thiamine plays a role in many metabolic reactions in the body such as glucose breakdown and branched-chain amino acid metabolism.

Vitamin B2 (riboflavin): Riboflavin produces FAD+, an important energy carrier in the body that helps produce ATP, the energy currency of our cells.* Riboflavin is also a necessary cofactor for the de novo synthesis of NAD+ from tryptophan as well as methylenetetrahydrofolate reductase, an enzyme which is crucial for the recycling and function of folate (vitamin B9) [96-98].* In addition, riboflavin plays an important role in recycling the toxic byproduct homocysteine from the blood [98].*

Vitamin B3 (niacin): Niacin comes in several forms. Niacin increases levels of NAD+ either from niacin/nicotinamide or the salvage pathway via niacinamide. NAD+ is another important energy carrier as well as cofactor for the longevity genes known as the sirtuins. We use two forms of niacin in our formulation to support healthy NAD+ levels.

Vitamin B5 (pantothenic acid): Pantothenic acid helps turn food into fuel for the body as an important molecule known as coenzyme A and can help maintain a healthy digestive tract.*

Vitamin B6 (pyridoxal-5-phosphate): Vitamin B6 is a crucially important B vitamin. During development, B6 plays a role in brain development.* Vitamin B6 also serves as an essential cofactor in the production of GABA, a calming neurotransmitter, serotonin, a crucial neurotransmitter for mood and sleep, and dopamine, a vital neurotransmitter for motivation and mood.* Our vitamin B6 is found in the active form pyridoxal-5-phosphate, rather than the more commonly used pyridoxine HCL. Pyridoxal-5-phosphate is a safer form of vitamin B6 since it does not have to be activated by the liver and is not associated with the side effect of sensory neuropathies of its counterpart pyridoxine at higher doses [99].* It may also have increased benefits on neurological function in comparison to pyridoxine [100-101].* In addition, pyridoxine has been shown to actually inhibit the active form, pyridoxal-5-phosphate which may explain its side effects [99].* Highlighting our commitment to safety, we make sure to use pyridoxal-5-phosphate in all our supplements so the risk of any adverse effects is minimized.* Pyridoxal-5-phosphate is also a cofactor in the synthesis of NAD+ via the de novo synthesis pathway and increased NAD+ serves as a cofactor for sirtuins.*

Vitamin B7 (biotin): Biotin has benefits for your skin, hair, and nails as well as metabolic reactions in the body.* Biotin is a component of carboxylation enzymes as well as the function of over 2000 human genes [102].* Mitochondria also utilize biotin for energy production.*

Vitamin B9 (Activated Calcium 5-Methyltetrahydrofolate): Our folate is found in the active methylated form, which is crucial since up to 40% of the population or more has a genetic mutation not allowing them to convert folate to its active form efficiently. Folate is an essential vitamin for pregnant women, healthy DNA synthesis, repair, and expression, as well red blood cell production.* Healthy levels of folate in the brain can play a role in a healthy mood and synapses and the activated form is crucial for the production of mood neurotransmitters in the brain.*

Vitamin B12 (methylcobalamin): An essential vitamin, vitamin B-12 supports red blood cell production, DNA synthesis, energy production, and nerve function.* The body can store up to 3-4 years’ worth of B12 in the liver. It is an essential component of myelin, the sheath around our nerves that helps them effectively transmit signals across their axons. Vitamin B12 can also support healthy energy, mood, and memory.* It is also crucial for the detoxification homocysteine from the body.* Our B12 of choice is methylcobalamin, the active form in the body compared to lower quality cyanocobalamin forms commonly found on the market.*

Vitamin A (retinyl palmitate): Vitamin A is an essential antioxidant for vision and immune system function, and a constituent of visual pigments.

Vitamin C (ascorbic acid): Healthy levels of vitamin C act as an antioxidant that can also boost the function of the immune system. Vitamin C is essential to the production of collagen, therefore making it an important component of healthy skin. It is also necessary to produce important neurotransmitters.

Vegan Vitamin D3 (VegD3®) (cholecalciferol): Vitamin D is an integral vitamin that we get from the sun and our diets. Our Vitamin D3 (VegD3®) has a proven clean supply chain, clean sourcing, and is vegan society approved! Our D3 is sourced from micro-algae unlike the sticky greasy secretions of sheep's sebaceous glands that most Vitamin D's on the market are from(gross!). Vitamin D has been shown to play a vital role in maintaining and protecting your gut barrier which promotes decreased inflammation [103-113].* Vitamin D also plays an important role in healthy calcium and phosphorus metabolism in the body and in the production of strong and healthy bones.* In addition, several studies have also shown an association between higher Vitamin D and longer telomere lengths, the protective caps on the ends of our chromosomes (genetic material) that progressively shorten as we age [114-116].* There is also some evidence for the role of vitamin D in immunity, brain function, and mood [117]. *

Vitamin E (d-alpha tocopherol): A powerful antioxidant, vitamin E protects our cell membranes from oxidation and damage. * Vitamin E also helps promote skin, hair and nails health. * Our vitamin E is in the natural d-alpha tocopherol form vs the synthetic dl-alpha tocopherol form. *

Vitamin K (phytonadione): Vitamin K is essential to produce clotting factors such as prothrombin and coagulation factors 7, 9, and 10 that protect you from bleeding.* It also has a role in regulating calcium metabolism and bone health.* Our vitamin K is in the natural K1 form that is found in our diet.*

70+ trace minerals from Ancient Peat (from ElevATP®): ElevATP® is composed of a water extract of ancient peat that contains over 70 trace minerals including sulfur, magnesium, manganese, calcium, phosphorus, potassium, zinc, silicon, iron, and more [13].* Similar to Shilajit Resin found in the rocks of the himalayas, ElevATP® boosts vitality and supports adaptivity.*

Zinc is a crucial component of over 300+ enzymes in the body as well as structural proteins. This vital mineral is known for its ability to support immune function as well as its role in wound healing and skin health. Zinc also plays a role in maintaining healthy hormone levels such as testosterone, estrogen, and progesterone.* Our blend supplies 100% of the DV of zinc.

Chromium picolinate is an effectively absorbed form of chromium, a crucial mineral for health.* Chromium supports healthy blood sugar levels as a component of chromodulin, which helps insulin perform its function in telling our cells to take in glucose.* Chromium can also play a role in reducing and balancing food cravings [93-95].* Our formula provides a generous 500 mcg, 1429% of the DV, of this vital mineral.